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For over 150 years, the ASPCA has worked tirelessly to put an end to animal abuse and neglect. We are a national leader in the areas of rescue, adoption and welfare, and your tax-deductible donation will help fight cruelty and make a life-changing difference for animals across America. Thank you for making the ASPCA and the animals we serve a part of your life.

For more than 70 years, Humane World for Animals—formerly called the Humane Society of the United States and Humane Society International—has been a leader of the animal protection movement, tackling the root causes of animal cruelty and suffering to drive permanent change and create a better world for all animals around the globe.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

To eliminate pet overpopulation, ensure the care and protection of pet companions and improve the quality of life for economically challenged, disadvantaged and underserved pet guardians by providing referral and financial assistance for spay/neuter and veterinary medical procedures together with other animal/human bond enriching programs.

Guide Dogs of America empowers people who are blind and visually impaired to live with increased independence, confidence and mobility by providing expertly matched guide dog partners.

Wags and Walks is a community of dog lovers working to promote shelter dogs as the best dogs in the world through advocacy of our unique family-friendly foster and adoption programs. Wags and Walks is dedicated to rescuing family-friendly dogs from shelters and finding them suitable permanent homes. Working with committed volunteers, foster homes, veterinarians, and trainers, we are able to rescue hundreds of dogs every year and provide them with loving temporary care while finding them well-matched, carefully screened forever homes.

The Maui Humane Society's mission is to protect and save the lives of Maui's animals, accepting all in need, educating the community, and inspiring respect and compassion towards all animals.

Pet Rescue And Adoption Is Primary Purpose. Adopt-A-Pet, Inc. also provides medical care and spays and neuters all adoptable animals.

Chartered in 1934, the Animal Defense League of Texas (ADL) is the oldest no-kill shelter for abandoned, abused, or neglected dogs and cats in South Central Texas. Through the operation of two facilities, a centrally located 12-acre campus and the city-owned Paul Jolly Center for Adoptions, ADL saves the lives of vulnerable animals primarily originating from the most poverty-stricken communities in San Antonio. A full veterinary hospital housed on the main campus provides spay/neuter surgeries, vaccinations, and microchipping for all pets in ADL’s care. In addition, ADL performs specialized surgeries for animals with complex medical conditions and is the first organization to provide no-cost mobile wellness clinics to historically underserved areas. ADL’s partnership with Animal Care Services (ACS) is instrumental in helping the City of San Antonio back to achieving a “No-Kill” status.

WWF's mission is the conservation of nature. Using the best available scientific knowledge and advancing that knowledge where we can, we work to preserve the diversity and abundance of life on Earth and the health of ecological systems by protecting natural areas and wild populations of plants and animals, including endangered species; promoting sustainable approaches to the use of renewable natural resources; and promoting more efficient use of resources and energy and the maximum reduction of pollution. We are committed to reversing the degradation of our planet's natural environment and to building a future in which human needs are met in harmony with nature. We recognize the critical relevance of human numbers, poverty and consumption patterns to meeting these goals.

Raising public awareness of wildlife preservation and protection needs and endeavors through music, film, and video.

Heifer International's mission is to end hunger and poverty while caring for the Earth in a sustainable way by supporting and investing alongside local farmers and their communities. Since 1944, Heifer has helped transform more than 52 million households by working in partnership with the communities we serve. Our programs support entrepreneurs around the world, creating lasting change from the ground up. It begins with a seed investment of livestock or agriculture, followed by mentorship to help project participants build a business, and ultimately to gain access to supply chains and markets. These families are able to earn a living income and continuously lift up their communities as they train the next generation of leaders. By supporting and training the world's farmers, ranchers, and female business owners, we're investing in a new breed of success. Heifer International by the numbers: *Currently operating in 19 countries *Over 1M active participant households in Heifer programs *Over 9M people trained since 2012 *67% of Heifer program participants in 2024 were women