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Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Through education and outreach we support those affected by Lewy body dementias, and promote research for a cure.

Fuck Cancer is a 501 (c)3 nonprofit in the United States and a registered Canadian charity dedicated to improving health outcomes by providing early detection, prevention, and support programs that advance health equity for individuals and communities affected by cancer. Fuck Cancer believes that people diagnosed with cancer, their families and their support network should have equitable access to early detection, prevention, and psychosocial support.

RAINN (Rape, Abuse & Incest National Network) is the nation's largest anti-sexual violence organization and was named one of "America's 100 Best Charities" by Worth magazine. RAINN created and operates the National Sexual Assault Hotline (800.656.HOPE and online.rainn.org) in partnership with more than 1,100 local rape crisis centers across the country and operates the DoD Safe Helpline for the Department of Defense. RAINN also carries out programs to prevent sexual violence, help victims and ensure that rapists are brought to justice.

Memorial Sloan-Kettering Cancer Center is dedicated to leading the fight against cancer, individually focusing on each patient and creating an impact on cancer treatment and the biomedical research agenda around the world. As one of the world's premier cancer centers, Memorial Sloan Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between its physicians and scientists is one of its unique strengths, enabling it to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future.

The American Kidney Fund fights kidney disease on all fronts as the nation's leading kidney nonprofit. We work on behalf of the 37 million Americans living with kidney disease, and the millions more at risk, with an unmatched scope of programs that support people wherever they are in their fight against kidney disease — from prevention through post-transplant living.

The mission of The Lustgarten Foundation is to advance the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer; and to provide patients and families with the information they need to make informed decisions about their care.

Established in 1985, The ALS Association is dedicated to leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support. The Association builds hope and enhances the quality of life while aggressively searching for new treatments and a cure, through global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships.

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

OMF’s mission is to accelerate and enhance scientific research, advocacy, and awareness of ocular melanoma and to provide education and support to patients, their families, and healthcare professionals. For patients and their loved ones, OMF aspires to be the top destination for up-to-date OM-related educational information, a meeting place, and advocacy resource. For doctors and researchers, OMF strives to be the connective tissue, facilitating interdisciplinary cancer research. The goal of OMF is to have there exist accessible and effective treatments for ocular melanoma and, one day, a cure

Our mission is a preferential option for the poor in health care. By establishing long-term relationships with sister organizations based in settings of poverty, Partners In Health strives to achieve two overarching goals: to bring benefits of modern medical science to those most in need of them and to serve as an antidote to despair. We draw on the resources of the world's leading medical and academic institutions and on the lived experience of the world's poorest and sickest communities. At its root, our mission is both medical and moral. It is based on solidarity, rather than charity alone. When our patients are ill and have no access to care, our team of health professionals, scholars, and activists will do whatever it takes to make them well- just as we would do if a member of our own families, or we ourselves, were ill.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.