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In the fight for a DIPG/DMG cure, we help patients and families by funding game-changing research and providing navigation throughout their journey.

Assist ME enhances the lives of people with low-to-no insurance in the Charlotte metro and surrounding communities who have lost mobility by providing them with the mobility equipment they need to regain their independence. Our goal is to help those in need get back to doing the things they love and living life to the fullest. Double your donation! Check your place of business policy for matching donations and request Assist ME be added to the deserving nonprofits that can be matched.

At Fred Hutch, world-leading scientists, clinicians, and experts are working together to prevent and eliminate cancer and infectious diseases. From improving cancer diagnosis, treatment, and care to finding new ways to stop HIV, herpes, COVID-19, and other diseases, our research improves and saves lives.

The mission of The University of Texas MD Anderson Cancer Center is to eliminate cancer in Texas, the nation and the world through outstanding programs that integrate patient care, research and prevention and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

UMDF's mission is to promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and provide support to affected individuals and families.

Guiding Eyes for the Blind--Provides guide dogs for the blind

New Directions believes that people who have disabilities deserve the same opportunities in life that others expect and enjoy. Our profoundly enriching travel programs expand the self-esteem of every traveler. Whole new worlds of understanding open for both participants and the general population. Through these unique programs, people with disabilities are increasingly understood, appreciated and accepted as important and contributing members of our world. Changing the way the world views disability— one adventure at a time.

Our mission is to advance the awareness and treatment of Angelman Syndrome through education and information, research, advocacy, and support for individuals with Angelman Syndrome, their families, and other concerned parties.

FirstHealth of the Carolinas is a not‑for‑profit health system that provides comprehensive hospital and community‑based health services across the mid‑Carolina region. It supports patient care programs (including cancer care, hospice/palliative care and community health initiatives), workforce development, and access to care regardless of a person’s ability to pay.

Our mission is to empower those affected by domestic violence and advocate for social change through support, education and outreach.

NORD represents 1 in 10 Americans who have rare diseases with programs of advocacy, education, research and patients services. It serves as the voice of the rare disease community on important issues of public policy. It also provides information on rare diseases in understandable language for patients and their families, with referrals to support groups and other helpful resources. It encourages research on new diagnostics and treatments and administers patients assistance programs. NORD mentors rare disease support groups so that they can more effectively help their members. It serves as the point of connection between the patient community and key government agencies, such as the National Institutes of Health (NIH) and Food and Drug Administration (FDA). Nearly 150 patient organizations are members of NORD and look to NORD for guidance, mentoring and leadership.

RSRT was launched in 2008 to drive research toward a cure for Rett Syndrome and related MECP2 disorders. Our mission is urgent: 15,000 girls and women in the United States and 350,000 globally live with the agonizing symptoms of Rett Syndrome.