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The mission of Doctors Without Borders/Médecins Sans Frontières (MSF) is to provide impartial medical relief to the victims of war, disease, and natural or man-made disaster, without regard to race, religion, or political affiliation. A non-profit, self-governed, member-based organisation, MSF's global reach is demonstrated by a presence in over 72 countries and territories with medical humanitarian projects, 9,904,200 medical consultations conducted by humanitarian teams, and 877,300 patients admitted to MSF hospitals or clinics around the world.

As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

St. Jude Children's Research Hospital seeks to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of their founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. St. Jude’s strives to be the world leader in advancing the treatment and prevention of catastrophic diseases in children, by providing outstanding patient care; conducting basic, translational and clinical research designed to elucidate biological mechanisms, understand disease pathogenesis, improve diagnosis, enhance treatment outcome, prevent diseases and minimize adverse consequences of treatment; and by educating health care and scientific research professionals. Treatments invented at St. Jude have helped push the overall childhood cancer survival rate from 20% to more than 80% since it opened more than 50 years ago.

UNICEF's mission is to help very child thrive, all over the world. Over eight decades, it has built an unprecedented global support system for the world’s children. UNICEF relentlessly works day in and day out to deliver the essentials that give every child an equitable chance in life: health care and immunizations, safe water and sanitation, nutrition, education, emergency relief and more. UNICEF USA advances the global mission of UNICEF by rallying the American public to support the world’s most vulnerable children. Through advocacy, education and fundraising in the United States. The organization's Impact Fund for Children provides opportunities for social impact investors seeking to make a difference in the survival and development of children.

To conserve and restore Maunalua Bay by informing, engaging, and empowering the community by forming strong partnerships with government and non-government organizations.

Be The Bridge's mission is to empower people and culture towards racial healing, equity and reconciliation. Our vision is that people are equipped to flourish and grounded in truth. They are no longer conditioned by racialized society. People and organizations are aware and responding to the racial brokenness and systemic injustice in our world.

Our mission is to prepare the next generation of leaders through higher education enriched by continuous training in service and ethics.

Fibershed's mission is to provide experiential education that both generates awareness, and teaches the necessary skills within our community to build and sustain a thriving bioregional textile culture that functions hand-in-hand with principles of ecological balance, local economies, and regional organic agriculture.

The mission is to provide education assistance, workforce development, and job opportunities to incarcerated women as well as ex-offenders, who are sincere about working hard to change their mindset and to become productive citizens.

The Vineyard is dedicated to nurturing the voices of daring artists and to developing and producing work that challenges all of us to see ourselves and our world from new perspectives, and which pushes the boundaries of what theatre can be and do.